glp 1 es bueno o malo La Verdad sobre el GLP-1: El Fármaco que Revolucionó la Pérdida de Peso y la Diabetes Peligros de los parches GLP-1

[DOI] [PubMed] [Google Scholar] [123].Buse JB, Nauck M, Forst T, Sheu WH, Shenouda SK, Heilmann CR, Hoogwerf BJ, Gao A, Boardman MK, Fineman M, Porter L, Schernthaner G, Exenatide once weekly versus liraglutide once daily in patients with type 2 diabetes (DURATION-6): a randomised, open-label study, Lancet, 381 (2013) 117124

However, compounded drugs are not FDA-approved and may be associated with higher safety concerns and product quality issues

****** confidence can take a hit

Int J Obes 34:16441654 Maggard-Gibbons M, Maglione M, Livhits M et al (2013) Bariatric surgery for weight loss and glycemic control in nonmorbidly obese adults with diabetes: a systematic review

Preclinical evidence has suggested that GLP-1R agonists can suppress hepatocellular inflammation and increased oxidative stress indirectly through several cellular pathways that are, in part, independent of weight reduction, since hepatocytes, Kupffer cells, and stellate cells do not express GLP-1Rs [7985]