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Some patients may qualify for one product under one pathway and another product under a different one

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While little is known about the role of this GLP-1R population, a function of the Brunner's glands is to secrete mucus to lubricate the intestinal wall and, as GLP-1 has been suggested to be a positive regulator of gut-barrier function, GLP-1 may act on these glands to increase mucus secretion, thereby decreasing inflammation and protecting against intestinal damage

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GLP-1 increases heart rate despite cervical vagotomy, autonomic ganglion blockade, and HCN channel blockade Next, we evaluated if the parasympathetic nervous system, or the combined autonomic nervous system, is involved in the GLP-1-induced increase in heart rate