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This is the first step in being able to use someones genetic make-up to help us improve that decision-making process. This work represents the first detailed look at GLP-1 resistance, although its underlying cause is still unknown

This effect is reminiscent of other weight-loss meds

Published studies suggest retatrutide produced larger mean body-weight reductions at top reported doses than tirzepatide in cohorts with obesity, although direct head-to-head trials have not been published at time of writing

5,6 Similarly, individuals with continuous enrollment in an insurance plan for one year before and one year after their index diagnosis of T2DM were included