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Wet (Neovascular / Exudative) Macular Degeneration Prevalence: ~1015% of AMD cases Pathophysiology: Abnormal choroidal neovascularization (CNV) under macula Leakage hemorrhage, exudation rapid central vision loss Clinical Features: Sudden or rapid decrease in central vision Metamorphopsia (straight lines appear wavy) Central scotomas May have subretinal hemorrhage Progression: rapid severe central vision loss if untreated Management: Intravitreal anti-VEGF injections (ranibizumab, bevacizumab, aflibercept) Laser photocoagulation (rarely, specific cases) Low-vision aids Dry AMD: slow, painless central vision loss, drusen present Wet AMD: rapid central vision loss, metamorphopsia, hemorrhage common Wet AMD is vision-threatening and requires anti-VEGF therapy Peripheral vision usually preserved in both types Summary Macular degeneration causes central vision loss

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Decreased bone mineral density with long-term use

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