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At the molecular level, a diverse array of factors, including non-coding RNAs (e.g., miR-522, LncRNA LASTR), regulatory proteins (e.g., USP7, ATF3, CDO1), and Helicobacter pylori infection (through virulence factors such as CagA), precisely modulate core ferroptosis pathways involving ALOX15, SLC7A11, GPX4, and the NRF2/xCT axis (113117)

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Efficacy and safety of once-weekly dulaglutide versus insulin glargine in mainly Asian patients with type 2 diabetes mellitus on metformin and/or a sulphonylurea: a 52-week open-label, randomized phase III trial