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A review of therapeutic options for managing the metabolic aspects of polycystic ovary syndrome

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GLP-1R agonists also demonstrate neuroprotective effects, including reduction of neuroinflammation, oxidative stress, and neuronal apoptosis, with emerging evidence for benefit in neurodegenerative diseases such as Parkinsons and Alzheimers disease [75, 76]

For researchers currently using retatrutide, the best approach is informed engagement

However, considering its important effects on innate immunity, long-term inhibition of the inflammasome comes with a risk of infection [10], which limits the clinical application of NLRP3 inflammasome inhibitors