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By increasing GLP-1 activity, it can reduce feelings of hunger and promote feelings of fullness, which can help individuals to stick to their weight loss goals

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Wong C.K., Yusta B., Koehler J.A., Baggio L.L., McLean B.A., Matthews D., Seeley R.J., Drucker D.J

Ongoing studies continue to uncover new potential health impacts, both positive and negative

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Some may tolerate semaglutide or tirzepatide better, particularly given retatrutide's higher GI side effect rates and the new dysesthesia safety signal