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Description
It impacts around 18% of people with diabetes and exhibits a higher prevalence than in those without diabetes

Lancet 372 , 12401250 (2008)

With Foundayo, we now have an oral option that delivered an average of 12.4% weight loss at the highest dose in clinical trials addressing both the clinical realities of obesity and the practical challenges patients face every day, Horn noted

All licensed GLP-1 receptor agonists are administered either as subcutaneous injections or, in limited cases, as oral tablets (such as oral semaglutide, marketed as Rybelsus)

The likely mechanism is that GLP-1 receptor agonists slow gastric emptying and reduce peristalsis the rhythmic muscular contractions that move stool through the colon
