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Am J Med Sci 368:579588

Direct impact can damage fragile peptide structures

This effect is thought to involve mechanical stimulation of visceral sensory nerves due to gastric distension, as well as delayed digestion and absorption caused by dietary fiber

Compared to GLP- 1 receptor mono-agonists and GLP- 1 receptor/GIP receptor co-agonists, optimized triagonists improve energy expenditure and restore body weight in DIO mice

Could this be answered fairly simply on a whole body level by examining DXA data in conjunction with deuterated water data to provide info on total body water
