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Taking multiple doses or timing your doses appropriately can help you manage these rebound effects

In the brain, GLP-1 secreted from intestinal cells can be absorbed into the brain, and GLP-1 secreted from neurons remains in the CSF (Holscher, 2012)
Site-specific knockdown of GLP-1R in the MHb or pharmacological antagonism of GLP-1Rs in the IPN increased nicotine intake and restored preference for nicotine-paired environments

2023 Jan-

As more medications arrive, the more useful question is which one suits which person, and what someone is doing alongside it to make the weight loss last
