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This is a critical issue, as a decrease in muscle mass leads to a reduction in basal metabolic rate [41, 42], which could hinder the long-term benefits of obesity treatment by impairing the overall metabolic profile

[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Smits M.M., Tonneijck L., Muskiet M.H., Kramer M.H., Pouwels P.J., den Pieters-van Bos I.C., Hoekstra T., Diamant M., van Raalte D.H., Cahen D.L

By reducing fat absorption, it can help create the calorie deficit needed for gradual and sustainable weight loss

Exenatide improves excessive daytime sleepiness and wakefulness in obese patients with type 2 diabetes without obstructive sleep apnoea

In addition, GLP-1RAs have demonstrated a clinically significant benefit in terms of prevention of cardiovascular and renal diseases but also a significant impact in a spectrum of other conditions [1215]