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(28) The crude incidence rates of LLA were 6.1 per 10,000 person-years for GLP-1 receptor agonists, 1.5 for SGLT-2 inhibitors, 4.6 for DPP-4 inhibitors, and 1.9 for older agents

The accumulated evidence from CVOTs has not only informed clinical practice guidelines but has also empowered healthcare providers with a valuable therapeutic option for T2D patients who have high cardiovascular risk

In May 2026, At the EASL Congress 2026, MetaVia presented promising late-breaking Phase 1 clinical trial results for DA-1726, an investigational dual GLP-1 and glucagon receptor agonist under development for obesity and Metabolic Dysfunction-Associated Steatohepatitis (MASH)

Dose adjustments may occur after the initial 3 months

And as demand continues to grow, what factors will determine whether patients can start and adhere to treatment long term