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The concern is purely mechanicalrelated to absorption rather than metabolism
"The long-term impact is bigger than weight loss
Glucagon-like peptide-1 receptor agonists and risk of parkinsons disease in patients with type 2 diabetes: a population-based cohort study

They can be a powerful part of a plan to achieve and maintain a healthy weight, he says, but the drugmakers and the FDA should do more to educate consumers about the side effects

Ongoing monitoring is recommended during treatment