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Semaglutide GLP-1 drugs facing the challenges in oral administration, injection administration can result in decreased patient compliance and therapeutic efficiency

In a study comprising 16 patients with T2DM and 12 non-diabetic controls, flow-mediated vasodilation was enhanced in both groups by GLP1 infusion of 0.4 pmol/kg/min, administered during a 2-hour hyperglycemic clamp [106]

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