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Both medications are studied at therapeutic doses in clinical trials

Nat Rev Endocrinol 19 , 164176 (2023)
Inflamm Bowel Dis (2008) 14(3):3107.10.1002/ibd.20328 154 MoranGWPennockJMcLaughlinJT

This residue is highly conserved in Drosophila Notch and vertebrate Notch proteins, but is absent in LIN-12 and GLP-1, even though the surrounding context is conserved
