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Description
Importantly, rates of gastrointestinal adverse events were similar between groups

Differences in treatment response to a total diet replacement intervention versus a food-based intervention: a secondary analysis of the OPTIWIN trial
Metabolic adaptation
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Some compounding pharmacies have created oral versions in the form of drops, capsules, or sublingual tablets, but these formulations have not been evaluated or approved by the FDA

[DOI] [PubMed] [Google Scholar] 28.Marathe CS, Rayner CK, Jones KL, Horowitz M
