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Synaptic Dysfunction and Memory Loss in Depression and Its Relation to GLP-1 In patients with depression, neural circuits are impaired as a result of aberrant communication between neurons (Williams, 2016)

Treatment with Januvia at 100 mg daily provided significant improvements in A1C, FPG, and 2-hour PPG compared to placebo (Table 3)

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The three primary outcome measures were intracranial pressure at 2.5 h, 24 h and 12 weeks and alpha set a priori at less than 0.1
