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However, no retrospective epidemiological studies can provide definitive answers, and nausea, vomiting and diarrhoea remain the most clinically relevant adverse effects of these drugs, compromising long-term adherence.

Negli ultimi anni si assistito a un crescente interesse per nuove modalit di gestione del peso corporeo, anche grazie alla diffusione di una nuova classe di farmaci, ovvero gli agonisti del recettore del GLP-1.

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A pivotal moment occurred in October 2022, just four months after Mounjaros launch, when Elon Musk admitted on Twitter (X) that taking Wegovy was his secret for looking fit and healthy. The post, and a subsequent tweet in 2024 that he was taking Mounjaro, went viral and sparked widespread curiosity around GLP-1s and their effectiveness on weight loss