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Key findings of the study are as follows: 76 of 145 410 patients (incidence rate 1.33 events per 10 000 person years) treated with GLP1 receptor agonists and 184 of 291 667 patients (incidence rate 1.46 events per 10 000 person years) treated with DPP4 inhibitors developed thyroid cancer

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This investigation utilizes the FAERS database to conduct a large-scale pharmacoepidemiologic analysis, aiming to generate robust real-world evidence regarding the safety profile of GLP-1 receptor agonist and metformin combination therapy through systematic evaluation of reported adverse events

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