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Hydration is critical, since loose stools increase fluid and electrolyte loss

There were no significant differences between subgroups in the number of patients achieving HbA1c 50%) was used to measure heterogeneity

Many provincial drug plans do not yet cover these medications for weight management, making out-of-pocket costs substantial at approximately $400-500 CAD monthly

Online forums and nootropics websites often recommend very low doses in the range of 0.5 mg per day for cognitive benefits

It is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), and in those with a prior serious hypersensitivity reaction to tirzepatide