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Description
DIU, diuretic
The linker ensures selective cleavage and provides the prospect of lowering systemic toxicity of the conjugate

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By synthesizing transcriptomic, pharmacokinetic, signaling, and pharmacovigilance findings into a coherent mechanistic framework, this narrative review addresses an unrecognized area of GLP-1 biology and provides the first integrated hypothesis on how prolonged GLP-1R activation could disrupt salivary gland function
PMID 34159571
