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The study, published in Nature Health , covers more than half a decade of posts from nearly 70,000 Reddit users and highlights two main classes of symptoms that warrant further study: reproductive symptoms, including irregular menstrual cycles, and temperature-related complaints, such as chills and hot flashes

Unlike GLP-1 agonists, berberine does not typically cause nausea through delayed gastric emptying, though gastrointestinal discomfort remains the primary tolerability concern

However, they are not FDA approved to treat hyperphagia, and most of the newer GLP-1s (Ozempic/semaglutide, Mounjaro/tirzepatide, and others) have not been studied in individuals with PWS

GLP-1 RAs are known to have a beneficial effect on lipid profile and blood pressure (BP)

The compounded semaglutide fridge life guide covers ideal storage conditions in more detail