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Description
Never skip doses due to travel disruptions
In a cell culture replicon assay, the A5328S/V and S6799A substitutions did not affect nirmatrelvir activity (EC50 value fold changes were 0.3/0.2 and 0.7, respectively)
But for many, it helps you titrate down and sometimes get off of it completely or use it as a tool when you need to
FDA approved in 2005 for Type 1 and Type 2 diabetes [19]
The effect is small and borderline
