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It is possible that mechanisms other than the effects on incretin activity may underlie the beneficial effects of DPP4 inhibition in type 2 diabetes
Additionally, GLP-1 medications should be avoided in individuals with a personal or family history of medullary thyroid carcinoma or MEN 2A/2B, as well as those with active pancreatic cancer or pancreatitis

Gastric emptying was delayed, similarly to the effect observed under therapy with GLP-1RA (61)

nej.md/3JoNIh6 Editorial: Triple G Agonists A Home Run for Obesity
