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Diabetes, according to WHO, is a multifaceted metabolic condition marked by disruption in the body's management of glucose

doi:10.1038/s41398-019-0515-5 Paddon-Jones D, Westman E, Mattes RD, Wolfe RR, Astrup A, Westerterp-Plantenga M

Tirzepatide exhibits a dual effect given that it is a dual agonist: GLP-1 leads to the postprandial secretion of insulin and inhibits glucagon

Interestingly, supplementation of metformin with 1.5 mg dulaglutide per week in the treatment of T2MD in obese patients with severe impairment of glycosylated hemoglobin A1c (HbA1c) was reported to bring lasting benefits in the control of glucose metabolism and body weight (173)

Glucagon-like peptide-1 protects the murine hippocampus against stressors via Akt and ERK1/2 signaling