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Stromberg, Z

An open research question is whether GLP-1s, independent of any formal mindfulness practice, produce cognitive effects that resemble components of mindful eating

Potential evening downsides The biggest risk with evening dosing is forgetting

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Furthermore, loss of lean muscle mass, which can occur alongside fat loss if protein intake and resistance exercise are inadequate, further reduces metabolic heat production since muscle tissue is metabolically active and generates significant body heat even at rest