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doi: 10.1016/S0140-6736(99)04088-X 93 ChapmanCRVierckCJ
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The concept of taking a pill for weight loss makes it sound like a magic fix
The EMPA-KIDNEY trial enrolled a larger proportion of participants without diabetes mellitus and included individuals with lower mean eGFR (37.3 mL/min/1.73 m) and median UACR (329 mg/g) compared to DAPA-CKD
Conversion to NADH sustains mitochondrial electron transport, whereas NADPH supports reductive biosynthesis and glutathione-dependent antioxidant buffering [83]
