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Goodwin Cartwright Truveta, Inc , Bellevue, WA, Patricia J
Moreover, serotonin-induced hypoglycemia in mice was blocked by the nonspecific serotonin receptor antagonist cyproheptadine and the specific serotonin receptor 2 antagonist ketanserin.CONCLUSION Together these data suggest that increased postprandial serotonin may contribute to the pathophysiology of PBH and provide a potential therapeutic target.FUNDING National Institutes of Health (NIH) grant R01-DK121995, NIH grant P30-DK036836 (Diabetes Research Center grant, Joslin Diabetes Center), and Fundao de Amparo Pesquisa do Estado de So Paulo grant 2018/22111-2
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Tirzepatide is significantly GIP and weaker GLP-1 - and there is evidence that GIP is neuroprotective
