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Pharmaceutical GLP-1 receptor agonists are licensed for type 2 diabetes and specific obesity indications according to NICE guidance, requiring GP consultation and monitoring

Excess body weight can contribute significantly to elevated blood pressure

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Abrahamsson N, Borjesson JL, Sundbom M, Wiklund U, Karlsson FA, Eriksson JW

125,126 Moreover, the ultrastructure of hippocampal synapses is destroyed, 127 thereby reducing the hippocampal dendritic spine density