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Some data indicate that GLP-1 receptor agonists can help improve testosterone levels, particularly in men with obesity or type 2 diabetes

doi: 10.1016/j.exger.2009.12.004

Tirzepatide's dual mechanism allows for a higher dose ceiling because the GIP component modulates the gastrointestinal effects that would otherwise limit dosing

Clinical Frameworks: Defining Obesity Beyond Body Mass Index (BMI) An important milestone of 2025 was the publication of The Lancet Diabetes & Endocrinology Commission on the Definition and Diagnostic Criteria of Clinical Obesity

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