do i have to take glp 1 forever you GLP-1 medication forever?, There isn’t a simple yes-or-no answer. It depends on the patient, their body, and their long-term goals., In this video, @lisa_jewell_md_plasticsurgery The GLP-1 Trap: Your Jumpstart

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Important considerations include: GLP-1 agonists are generally well-tolerated in people with hypertension They do not typically cause dangerous drops in blood pressure Dehydration from gastrointestinal side effects (nausea, vomiting, diarrhoea) can occasionally affect blood pressure and kidney function, so maintaining adequate fluid intake is important If you take diuretics (water tablets), ACE inhibitors or ARBs for blood pressure, your doctor may monitor you more closely during the initial weeks of GLP-1 therapy Seek medical advice promptly if you experience persistent gastrointestinal symptoms that prevent adequate fluid intake NICE guidance (NG28) supports the use of GLP-1 agonists in people with type 2 diabetes who meet specific criteria, with preference for agents with proven cardiovascular benefits in those with established cardiovascular disease

Although GLP-1s primarily stimulate insulin secretion in a glucose-dependent manner (for instance, only in the presence of elevated blood glucose), hypoglycemia can still occur in certain situations such as insufficient food intake, excessive exercise, and particularly when used in combination with other antidiabetic agents, such as sulfonylureas or insulin

A small but genuinely helpful habit: Download a medication reminder app before your trip and update your alarm to reflect the time zone you're travelling to as soon as you land

Glucagon-stimulation of insulin secretion is preserved in islets isolated from -cell-specific GCGR KO mice but is attenuated upon treatment of these islets with exendin (939) [173]