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Advise women to inform their healthcare provider if they are pregnant or intend to become pregnant [ see Use in Specific Populations (8.1, 8.3)]

And unlike other diets, GLP-1s have something like a built-in guardrail, with users citing specific cravings and aversions

This creates a clinical flow where patients initiate on oral therapy, stabilize, and either remain on pills or step up to higher-efficacy injectables based on their clinical needs, a tiered treatment model that expands the overall market rather than simply redistributing it

GLP-1 agonists have emerged as promising therapeutic agents for diabetic cardiomyopathy through multiple protective mechanisms

Macias BR, Liu JH, Grande-Gutierrez N, Hargens AR