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The authors attributed the superiority specifically to the additive GIPR component, as semaglutide provides equivalent GLP-1R engagement at approved doses
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Liraglutide at 10 nM and 100 nM also promoted osteogenic differentiation in hBMSC and Human dental pulp stem cells (hDPSC) through enhancing ALP activity, mineralization and osteogenic marker expression [21, 27]
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Nauck M, Frid A, Hermansen K, LEAD-2 Study Group, et al

Quagliani, D., & Felt-Gunderson, P