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Zhuang, L

In conclusion, compound 20 in the biphenyl-substituted triazole group, as well as compounds 21 and 22 in the acetoxy- and monophenyl-substituted triazole groups, demonstrated the highest potency for inhibiting DPP-4 (99) (Figure 4)

GLP-1R is a B-class GPCR that acts on both Gq and Gs signaling, comparable to the other incretin hormone glucose-dependent insulinotropic polypeptides (GIPs), though they only activate the Gs signaling pathway

Thats probably more to do with weight loss than the direct effect of the drug itself, but regardless of where it comes from, Im freezing

It appears to be a news article or policy commentary piece about Medicare coverage decisions regarding GLP-1 medications rather than a peer-reviewed clinical study