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Participants also had to have at least one other underlying condition such as obesity, hypertension or heart disease and couldnt have used a diabetes drug within the past six months

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"Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial." Published in Nature Medicine, Accessed on November 13, 2023 at National Center for Biotechnology Information (NCBI)

Weight Loss Reduces Knee-Joint Loads in Overweight and Obese Older Adults With Knee Osteoarthritis. Arthritis & Rheumatism