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With oral sema removing the needle barrier, these numbers could multiply, and by the time Lilly mobilizes their own D2C channels, patients will already be stable on sema and we know that switching stable patients is very difficult

Ayoub I, Oh MS, Gupta R, McFarlane M, Babinska A, Salifu MO

Its the transition from: Premium, high-cost therapy Scalable, mass-market metabolic care If lower pricing aligns with oral delivery formats, GLP-1 could move from a niche weight-loss drug to a mainstream chronic treatment category

He, Y, Rodrigues RM, Wang X, Seo W, Ma J, Hwang S, et al

Lower starter doses may cost less, while higher maintenance doses generally increase the monthly expense