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Furthermore, a recent study of genetic variants associated with lithium responsiveness in bipolar disorder patients found a significant enrichment of genes involved in glutamatergic synapse neurotransmission, which included GSK3 and CAMK4 [175]

Practices should stock appropriate treatments for hypoglycemia, allergic reactions, and other potential complications

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This activation inhibits intracellular serine/threonine kinases, like JNK, which in turn reduces insulin receptor substrate (IRS)-1 serine phosphorylation, a major contributor to insulin resistance, and decreases atherosclerosis

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