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The protocol for this review was registered in the PROSPERO database under registration number CRD42018090829

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Search items included medication-related itemsGLP-1 receptor agonist, GLP-1RA, dual-agonist, and glucagon-like peptide-1 along with cardiovascular outcome-related items major adverse cardiovascular event, myocardial infarction, coronary artery disease, peripheral arterial disease, heart failure, hypertension, and atrial fibrillation. Studies were meticulously screened and included if they reported cardiovascular outcomes related to MACE, myocardial infarction (MI), CAD, PAD, HF, hypertension (HTN), or AF

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