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Abstract Purpose of Review This review explores the rationale and available evidence behind incretin-based therapies for metabolic dysfunction-associated steatotic disease (MASLD) and metabolic-associated steatohepatitis (MASH), focusing on glucagon-like peptide 1 (GLP-1) and glucagon (GCG) receptor dual agonists (GLP-1/GCG RAs)

Studies showed that beginning at .25 mg weekly, then titrating upward over 1620 weeks, reduced gastrointestinal side effects while building tolerance

These symptoms, while rare, warrant professional guidance to rule out individual sensitivity or dosing adjustments

She currently holds an appointment as adjunct associate professor at UTMB