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A disproportionality analysis (Godfrey et al., JEADV 2025) found a reporting odds ratio of 1.73 for tirzepatide (95% CI: 1.42 to 2.09), and as high as 2.46 for semaglutide

At USD 1,349 per month list price for Wegovy and USD 1,059 for Zepbound, monthly GLP-1 obesity drug costs create absolute financial barriers for the 62% of obesity patients enrolled in Medicaid, Medicare, or underinsured commercial plans without anti-obesity medication benefits

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Even then, the rules are a patchwork

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