semaglutide with metformin vs. Metformin for Weight Loss |
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However, both medications are mechanistically safe for the heart neither increases risk of serious arrhythmias or cardiac events in patients without pre-existing disease

Song et al., 2023

1,2,4 Wegovy already has cardiovascular outcomes data through the SELECT trial, which showed a 20% reduction in serious heart events
The Precision Peptide Genetic Test examines predispositions in GLP-1 and GIPR signaling pathways (including variants like GLP1R rs6923761 and GIPR rs1800437) that may help inform whether you are likely to benefit from sustained GLP-1 therapy
Always consult with a healthcare provider before starting or stopping any medication
