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Invited to give a presentation on GLUT2, he quickly gained the attention of people from Novo Nordisk when he briefly mentioned his work on the GLP-1 receptor at the end of his talk which he had not yet published

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The enzyme dipeptidyl peptidase-4 (DPP-4) rapidly degrades circulating GLP-1, which is why pharmaceutical versions are chemically modified to resist this breakdown and maintain therapeutic levels for extended periods

Cyclodextrins are generally considered safer in this regard, with toxicological studies confirming acceptable nasal tolerability at therapeutic concentrations

McKay, N
