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Shiiya, T

Administration of LPS, an endotoxin derived from Gram-negative bacteria that activates innate immunity and increases proinflammatory cytokines such as TNF-, IL-6, and IL-1, elevates circulating GLP-1 within 3 hours in mice and humans (57)

It's done from the multi-dose vial format, not the single-use pen, and only under provider guidance

Al-Nimer, Vian A
