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Room temperature limits: If necessary, an unopened Wegovy pen can survive at room temperature (46F to 86F) for up to 28 days
Additionally, liraglutide, orforglipron, semaglutide, and tirzepatide were associated with increased vomiting risk, while cagrilinitide and exenatide showed no significant increase

This may be the basis of the relatively low affinity of tirzepatide at the mGIPR since it is derived from the human GIP sequence

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