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CRB Group, a pharma engineering consultant, notes that short-term capacity additions (e.g

No anhedonia or fatigue : A documented side effect from these meds is anhedonia, the blunting of pleasure/joy, and some users report fatigue

PMID 31447084

Timing Considerations When Taking Semaglutide Blood donation requires adequate hydration, stable blood pressure, and a hemoglobin level above a minimum threshold

The pills haven't been compared head-to-head in a clinical trial, but in separate studies, the Wegovy pill showed average weight loss of 14% over 64 weeks, compared with 2% for a placebo, while orforglipron showed 11% weight loss over 72 weeks on its highest dose, compared with 2% for the placebo group