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Ferrannini G, Gerstein H, Colhoun HM, et al

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If you take 2 mg of retatrutide and feel minimal effects, increasing to 3 mg the following week means your body contains approximately 4 mg worth of the drug, not 3 mg

We've been using them safely in medicine for decades nicotine replacement, hormone replacement therapy (HRT), some pain medications, motion sickness drugs, certain heart treatments

Whilst it has a paracrine or endocrine role in the periphery, centrally GLP-1 is an important neuroendocrine agent