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They are rapidly inactivated by dipeptidyl peptidase-4 (DPP-4)
doi: 10.1016/j.jdiacomp.2014.01.012 73 BolliGBMunteanuMDotsenkoSNiemoellerEBokaGWuYet al
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Just make sure youre replacing what your body loses

Nausea is the most commonly-reported adverse effect, though it usually decreases over time as a patients tolerance toward GLP-1 administration increases [139]
