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Description
This is a toxic metabolite is speculated to cause the end-organ damage observed with DEG poisoning

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As a GLP-1 receptor agonist, this medication plays a key role in controlling blood sugar and supporting significant glp-1 weight loss

Investigation of the safety and efficacy profile of semaglutide and tirzepatide used in patients with T1D who have previously undergone allogeneic islet transplantation/pancreas transplantation and/or kidney transplantation for improving glucose control, reducing beta-cell glucotoxicity, mitigating the immunosuppressant-induced beta-cell dysfunction [152], preserving endogenous insulin secretion, preventing graft dysfunction and graft failure, promoting graft function and survival, and possibly reducing the required doses of immunosuppressants through anti-hyperglycemic actions and potential anti-inflammatory, antioxidant, immunomodulatory and beta-cell protective properties (stimulation of beta-cell proliferation and survival)