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ziyad al aly glp 1 Al-Aly, MD, FASN | Division of General Medicine & Geriatrics Ziyad Al-Aly, MD (@zalaly) /

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Understanding GLP-1 Medications and Illness GLP-1 receptor agonists work by mimicking a natural hormone that regulates blood sugar and appetite control

ziyad al aly glp 1 Al-Aly, MD, FASN | Division of General Medicine & Geriatrics Ziyad Al-Aly, MD (@zalaly) /

These medications are approved by the Food and Drug Administration (FDA) for the treatment of obesity or overweight with weight-related comorbidities

ziyad al aly glp 1 Al-Aly, MD, FASN | Division of General Medicine & Geriatrics Ziyad Al-Aly, MD (@zalaly) /

In contrast, the expression of GLP-1 mRNA in the colon tissues of mice in the model group decreased, and the content of GLP-1 in serum decreased

ziyad al aly glp 1 Al-Aly, MD, FASN | Division of General Medicine & Geriatrics Ziyad Al-Aly, MD (@zalaly) /

Now the confirmed mechanism of metformins hypoglycemic action is to inhibit hepatic gluconeogenesis and reduce hepatic glucose output through both AMPK-dependent (Song et al., 2001

ziyad al aly glp 1 Al-Aly, MD, FASN | Division of General Medicine & Geriatrics Ziyad Al-Aly, MD (@zalaly) /

Understanding its effects establishes the baseline against which all subsequent escalations are measured

ziyad al aly glp 1 Al-Aly, MD, FASN | Division of General Medicine & Geriatrics Ziyad Al-Aly, MD (@zalaly) /

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