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[DOI] [PubMed] [Google Scholar] 18.Thomas M.C., Brownlee M., Susztak K., Sharma K., Jandeleit-Dahm K.A.M., Zoungas S., Rossing P., Groop P.-H., Cooper M.E

In select cases, oral formulations exist but may be used for other indications

In 2014, the FDA approved the first of these drugs specifically for weight loss for people with a BMI of 30 and above or a BMI of at least 27 with one weight-related comorbid disease, which affects more than half the U.S

As such, discontinuing therapy solely based on normalized HbA1c may deprive patients, especially those with underlying cardiovascular or renal risk, of organ-protective effects that are both substantial and sustained
